What is the role of Apoptosis inhibitors in the pathophysiology of obesity?

Date:2023-03-08
Apoptosis, or programmed cell death, is a normal and necessary process of cell health and development, allowing damages or aged cells to be removed and replaced with healthy cells. However, certain drugs known as apoptosis inhibitors prevent apoptosis from taking place, resulting in the accumulation of unhealthy, aged, and unwanted cells in the body. This can cause cellular damage and lead to diseases, including obesity. Studies have found that apoptosis inhibitors play a role in the pathophysiology of obesity by promoting fat cell accumulation through impaired apoptosis in adipose tissue. This can lead to changes in body composition and may be a major contributing factor to weight gain and obesity.
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