How does myosin IIB enhance the process of retraction?
Date:2023-01-06
Myosin IIB plays a key role in the retraction process. It forms complexes with actin and myosin IIA and is responsible for the ATP-powered contraction of the actin filaments in the cytoskeleton that leads to cell retraction. Myosin IIB also serves to stabilize actin filaments and prevent them from collapsing during the retraction process. Additionally, Myosin IIB helps recruit and nucleate Arp2/3 complex formation, which is integral to the retraction process. By doing so, Myosin IIB helps to form new actin filament cross-links and facilitate the dynamic movement of actin filaments that leads to cell retraction.
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