What is the role of osteal macrophages in bone modeling?

Date:2023-02-27
Osteoclasts (osteal macrophages) are specialized macrophage cells that are involved in bone remodelling, especially during the formation of bones in developing organisms. These cells serve as demolition workers, taking apart older bone and leaving behind an empty space or a "bone cavity" that is then filled with calcium phosphate and other tissue to create new bones. Osteoclasts are also essential in maintaining the proper balance of minerals in the blood, as they dissolve old bones that contain excess minerals like calcium and phosphate. Additionally, they play an important role in the physiology of the immune system, removing dead cells and debris from the bone microenvironment.
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Is heterochromatin loss in old mice?

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