How do autoimmune disorders affect the lysosome?
Date:2023-01-06
Autoimmune disorders can affect the lysosome in several ways. In autoimmune diseases, the body’s own immune system attacks its own cells, and this can cause lysosomes to become damaged and dysfunctional. Furthermore, lysosomes may be unable to effectively break down proteins and other cellular debris due to elevated levels of proteins, which in turn can lead to the accumulation of toxic waste in the lysosome and throughout the body. This accumulation can lead to tissue damage and organ failure. Additionally, autoimmune disorders can lead to an increase in levels of oxidants, which can further damage lysosomal enzymes and lead to the accumulation of toxic compounds in the lysosome.
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