How do macrophages kill bacteria?

Date:2023-03-06
Macrophages use several mechanisms to kill bacteria including phagocytosis, the release of antimicrobial peptides, and the production of reactive oxygen species. In phagocytosis, the macrophage attaches to the bacteria and engulfs it in a process of endocytosis. Inside the macrophage, the engulfing vacuole is acidified, killing and digesting the bacteria. Antimicrobial peptides are proteins produced by the macrophage that puncture the outer membrane and cell walls of the bacteria, leading to cell death. Reactive oxygen species, such as hydrogen peroxide, superoxide, and hypochlorite, are also produced by macrophages. This oxidative burst can damage some bacteria and help the macrophage quickly kill bacteria within its vicinity.
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What is the excess credit hour surcharge?

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